某个不知名小镇，底下水突然被某种神秘物质所污染，进而污染整个镇子的饮用水。村民在不知情的情况下喝了污染水，很快就会变异成嗜血如命的丧尸。他们见人就咬，而被咬过的人也没过多久就变成丧尸的同类。小镇少年吉姆因为日常以可乐作为饮料，所以逃过一劫，但是他的妈妈却被感染。他想方设法带着尚在襁褓中的小妹妹逃出家门，夺路而逃，最终被小镇警察（罗伊·迪普伊 Roy Dupuis 饰）所救。警察尝试找到女儿，可他的女儿早已变成丧尸，对此这位父亲仍不离不弃。与此同时，相关部门全面封锁消息，并且派出两名双胞胎女杀手进入小镇，打算对相关知情者杀人灭口。 恐怖的氛围继续蔓延，幸存者越来越少，求生越来越难……
Two sisters living separate lives on different continents are reunited on a Mediterranean Island. The two barely have time to bond and revive family ties as Kate, the elder, meets a group of locals and agrees to an exciting ride on a hot air balloon. But disaster strikes and as the result of a freak accident, the balloon is carried far out to sea. Their cell phones out of range, and the balloon running out of gas, Kate and her friends are battling for their lives. While, back on land, the younger sister, Liz, has become an unwanted "material witness" to a crime. Matters then take a dramatic twist, one that will mark their lives forever.
